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Related Experiment Video

Updated: Mar 13, 2026

A Microplate Assay to Assess Chemical Effects on RBL-2H3 Mast Cell Degranulation: Effects of Triclosan without Use of an Organic Solvent

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Published on: November 1, 2013

Triclosan: an Instructive Tale.

Patrick J McNamara¹, Stuart B Levy^2,3

¹Department of Civil, Construction & Environmental Engineering, Marquette University, Milwaukee, Wisconsin, USA.

Antimicrobial Agents and Chemotherapy

|October 14, 2016

Summary

This summary is machine-generated.

The FDA banned 19 antimicrobial chemicals, including triclosan, from soaps. This ban addresses environmental risks, particularly the spread of antibiotic resistance driven by persistent chemicals like triclosan.

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Area of Science:

Environmental Science
Microbiology
Public Health

Background:

Antimicrobial chemicals, such as triclosan, have been widely used in consumer soaps.
Concerns exist regarding the environmental persistence and potential health risks associated with these chemicals.

Purpose of the Study:

To evaluate the implications of the FDA's final rule banning triclosan and 18 other antimicrobial agents from over-the-counter soaps.
To highlight the environmental risks posed by triclosan, specifically its contribution to antibiotic resistance.

Main Methods:

Analysis of the FDA's final rule on antimicrobial soaps.
Review of scientific literature on triclosan's environmental persistence and its effects on bacterial adaptation.
Assessment of the link between triclosan exposure and the development of antibiotic resistance.

Main Results:

The FDA has finalized a rule to remove 19 antimicrobial ingredients, including triclosan, from certain consumer soaps.
Triclosan is a persistent environmental chemical that exerts selective pressure on bacteria.
This pressure can drive the adaptation of bacteria, potentially promoting antibiotic resistance.

Conclusions:

The FDA's ban on triclosan in soaps is a crucial step in mitigating environmental risks.
Reducing the use of persistent antimicrobial chemicals like triclosan is essential to curb the spread of antibiotic resistance.
Immediate action is needed to halt practices that foster antibiotic resistance, especially when benefits are negligible.