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[Magnetic resonance imaging (MRI) in the diagnosis of optic neuritis and neuropathy]

Y Kakisu, E Adachi-Usami, S Kojima

    Nippon Ganka Gakkai Zasshi
    |February 1, 1989
    PubMed

    Insights

    Magnetic resonance imaging (MRI) is useful for diagnosing optic neuritis (ON), especially when caused by multiple sclerosis (MS). MRI detected abnormalities in most MS patients, aiding diagnosis even when visual field tests were normal.

    Area of Science:

    • Neurology
    • Radiology
    • Ophthalmology

    Background:

    • Optic neuritis (ON) is an inflammatory condition affecting the optic nerve.
    • Multiple sclerosis (MS) is a common cause of ON.
    • Accurate diagnosis of ON and its underlying cause is crucial for patient management.

    Observation:

    • MRI scans were conducted on 30 patients with optic neuritis (ON).
    • Twenty-one patients had ON attributed to multiple sclerosis (MS).
    • Nine patients had ON with undefined causes.

    Findings:

    • MRI revealed abnormalities in 17 of 21 MS patients, including lesions near ventricles, mid-brain, and spinal cord.
    • Increased MRI signals were observed in the visual pathway (optic chiasm to optic radiation) in 5 cases.
    • Abnormal MRI findings did not consistently correlate with Goldmann visual field defects.
    • In 3 of 9 ON cases with unknown causes, white matter hyperintensities were detected, suggesting potential future MS development.

    Implications:

    • MRI is a valuable diagnostic tool for optic neuritis, particularly in suspected multiple sclerosis.
    • MRI findings can identify central nervous system involvement beyond the optic nerve.
    • The study highlights MRI's utility in diagnosing MS and potentially predicting its development in ON patients.

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