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Published on: August 24, 2019
Effects of vitamin D supplementation on pulmonary function in postmenopausal women following an aquatic exercise
Rodrigo Nolasco1, Linda D F Moreira1, Danilo S Bocalini2
1Departamento de Medicina, Disciplina de Endocrinologia, Faculdade de Medicina, Universidade Federal de São Paulo (Unifesp/EPM), São Paulo, SP, Brasil.
Objective:
This study sought to investigate the effects of vitamin D supplementation and aquatic exercise on pulmonary function in postmenopausal women.
Materials And Methods:
This prospective and controlled study included 104 women (62 ± 6.5 years) divided into three groups: a control group lacking vitamin D and calcium supplementation which remained sedentary (CG; n = 17); a control group receiving vitamin D and calcium supplementation which remained sedentary (CDG, n = 33); and a group that completed aquatic exercises three times a week and received vitamin D and calcium supplementation (DTG, n = 54). Data before and after 6 months of the study were analyzed, including serum 25-hydroxyvitamin D (25(OH)D) and calcium concentrations, peak expiratory flow (PEF), forced vital capacity (FVC), and cirtometry.
Results:
We observed significant increases in 25(OH)D concentrations in CDG (52.9 ± 2.4 to 69.1 ± 2.2; nmol/L; p < 0.0001) and DTG groups (55.5 ± 3 to 71.5 ± 3 nmol/L; p < 0.0001). PEF increased by 7 ± 2% (p = 0.0080) in CDG group and 11 ± 2% (p < 0.0001) in DTG group, whereas FVC increased by 7 ± 2% (p = 0.0016) in the CDG group and 10 ± 2% (p < 0.0001) in the DTG group, whereas CG had no changes in any of these parameters. The increment value of cirtometry in DTG group (+43 ± 3%) were significantly (p < 0.0001) higher than those in CG (-4 ± 8%) and CDG (+4 ± 9%) groups.
Conclusion:
Our data suggest that vitamin D supplementation improves pulmonary function parameters in postmenopausal women.
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