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Updated: Mar 13, 2026
Novel RNA-Binding Proteins Isolation by the RaPID Methodology
Published on: September 30, 2016
Isolation and characterization of roridin E
Clark D Ridge1, Eugene P Mazzola1, Martyn P Coles2
1Office of Regulatory Science, Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, MD, 20740, USA.
Abstract:
The commonly occurring, high-cytotoxicity macrolide roridin E has been re-isolated from Stachybotrys chartarum and characterized by 1-D and 2-D NMR spectroscopy. Assignment of the spectral data for roridin E revealed differences from the accepted literature, and spectra are reported herein to aid in future identification. For the first time confirmation of structure was provided by a crystallographic solution for roridin E. Copyright © 2016 John Wiley & Sons, Ltd.
