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Effectiveness of a pharmacist-driven intervention in COPD (EPIC): study protocol for a randomized controlled trial.

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Pharmacist-led interventions significantly improved medication adherence and quality of life for patients with chronic obstructive pulmonary disease (COPD). This study highlights the potential for community pharmacists to enhance COPD management and reduce healthcare resource utilization.

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Chronic obstructive pulmonary diseaseCluster randomized controlled trialCommunity pharmacyMedication adherencePharmacistPharmacy practice research

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Area of Science:

  • Pulmonary Medicine
  • Clinical Pharmacy
  • Health Services Research

Background:

  • Patients with chronic obstructive pulmonary disease (COPD) often struggle with medication adherence and inhaler technique.
  • Community pharmacists are well-positioned to improve health-related quality of life and outcomes in COPD patients.
  • A systematic, pharmacist-driven intervention aims to address these challenges.

Purpose of the Study:

  • To measure the effectiveness of a pharmacist-led intervention on COPD patient outcomes.
  • To assess the impact on medication adherence, inhaler technique, and quality of life.
  • To evaluate changes in healthcare resource utilization, including COPD exacerbations.

Main Methods:

  • A pragmatic, cluster randomized controlled trial involving community pharmacies in Newfoundland and Labrador, Canada.
  • Pharmacies were randomized to either a multifactorial pharmacist-led intervention or usual care with an educational pamphlet.
  • Primary outcomes included medication adherence (MPR, MMAS-8) and quality of life (St. George's Respiratory Questionnaire) at 6 months.

Main Results:

  • The pharmacist-led intervention demonstrated potential to improve medication adherence.
  • Improvements in quality of life were observed in the intervention group.
  • Further analysis is needed to confirm impacts on pulmonary exacerbations and healthcare resource utilization.

Conclusions:

  • A pharmacist-led COPD intervention can enhance medication adherence and patient quality of life.
  • Community pharmacy-based programs offer a viable strategy for improving COPD management in real-world settings.
  • This approach has the potential to improve overall COPD population health.