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Draft Genome Sequence of Marine-Derived Bacillus subtilis TP-B0611, a Producer of Bacilosarcins and Amicoumacins
Hisayuki Komaki1, Akira Hosoyama2, Natsuko Ichikawa2
1Biological Resource Center, National Institute of Technology and Evaluation (NBRC), Chiba, Japan komaki-hisayuki@nite.go.jp.
Abstract:
Here, we report the draft genome sequence of Bacillus subtilis TP-B0611, which produces the isocoumarin-type compounds bacilosarcin and amicoumacin. The genome encodes three nonribosomal peptide synthetase (NRPS) gene clusters and one hybrid polyketide synthase (PKS)/NRPS gene cluster. The hybrid PKS/NRPS gene cluster was identified to be responsible for the biosynthesis of bacilosarcins and amicoumacins.
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