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A Murine Model of Muscle Training by Neuromuscular Electrical Stimulation

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Neurogenic muscle hypertrophy: a case report.

Hyun Ho Shin¹, Young Hoon Jeon², Seung Won Jang³

¹Department of Anesthesiology and Pain Medicine, Keimyung University School of Medicine, Daegu, Korea.

The Korean Journal of Pain

|October 15, 2016

Summary

Neurogenic muscle hypertrophy, a rare condition, can cause calf pain and enlargement. This case highlights the importance of considering nerve disorders in patients with unexplained lower limb hypertrophy.

Keywords:

Hypertrophy Muscle weakness Nervous system diseases Radiculopathy Spine Steroids

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Area of Science:

Neurology
Musculoskeletal Medicine

Background:

Muscular hypertrophy is typically associated with myopathic disorders.
Neurogenic causes of muscle hypertrophy are rare but documented.

Observation:

A 74-year-old woman presented with chronic right calf pain and hypertrophy.
Magnetic resonance imaging (MRI) revealed lumbar spinal stenosis (L4-L5) and fatty changes in the right gastrocnemius and soleus muscles.
Electrodiagnostic tests indicated polyradiculopathy affecting the 5th lumbar and 1st sacral nerves.

Findings:

The patient was diagnosed with neurogenic muscle hypertrophy secondary to lumbar spinal stenosis and polyradiculopathy.
The hypertrophy was attributed to fatty degeneration of specific calf muscles.

Implications:

This case underscores the importance of considering neurogenic etiologies in patients presenting with lower limb hypertrophy and pain.
Clinicians should consider neurogenic muscle hypertrophy in the differential diagnosis for unexplained calf enlargement and associated symptoms.