Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Estimating intervention effects in longitudinal studies.

J H Dwyer1, D P MacKinnon, M A Pentz

  • 1Institute for Health Promotion and Disease Prevention Research, University of Southern California School of Medicine, Pasadena.

American Journal of Epidemiology
|October 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Using Log-Linear Models for Longitudinal Data to Test Alternative Explanations for Stage-Like Phenomena: An Example from Research on Adolescent Substance Use.

Multivariate behavioral research·2016
Same author

Frequency of daily tooth brushing: predictors of change in 9- to 11-year old US children.

Community dental health·2014
Same author

Outcome of a tobacco use cessation randomized trial with high-school students.

Substance use & misuse·2009
Same author

Covariates of tooth-brushing frequency in low-income African Americans from grades 5 to 8.

Pediatric dentistry·2007
Same author

The protective influence of parents and peers in violence avoidance among African-American youth.

Maternal and child health journal·2002
Same author

Understanding environmental, situational and intrapersonal risk and protective factors for youth tobacco use: the Theory of Triadic Influence.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco·2002
Same journal

Correction to: Home dampness and molds and occurrence of respiratory tract infections in the first 27 years of life: the Espoo Cohort Study.

American journal of epidemiology·2026
Same journal

A SIMPLE AND POWERFUL TEST OF VACCINE WANING.

American journal of epidemiology·2026
Same journal

Association Between maternal body mass index, offspring growth and pubertal timing: results from a longitudinal birth cohort study.

American journal of epidemiology·2026
Same journal

Correction to: Developing a novel algorithm to identify incident and prevalent dementia in Medicare claims-the ARIC Study.

American journal of epidemiology·2026
Same journal

RE: advancing observational research on arts and health: theory-informed approaches using the RADIANCE framework.

American journal of epidemiology·2026
Same journal

Maternal Cesarean Section and Offspring ASD or ADHD Risk: A Nurses' Health Study II Analysis.

American journal of epidemiology·2026
See all related articles

This study addresses statistical challenges in longitudinal research on adolescent substance use interventions. It found a significant reduction in cigarette use among adolescents in intervention schools.

Area of Science:

  • Epidemiology
  • Biostatistics
  • Public Health

Background:

  • Longitudinal studies assessing disease risk factor interventions face statistical complexities.
  • These include ordered categorical outcomes, transition patterns, mixed units of analysis, incomplete randomization, and correlated measurements.

Purpose of the Study:

  • To demonstrate statistical solutions for common problems in longitudinal intervention studies.
  • To analyze the impact of the Midwestern Prevention Project on adolescent substance use (cigarettes, alcohol, marijuana).

Main Methods:

  • Proportional odds regression for ordered categories.
  • Conditional logistic models for transitions with interaction effects.
  • Logistic models using aggregated social unit data.

Related Experiment Videos

  • Conditional and unconditional models for effect magnitude.
  • Repeated measures logistic regression for correlated data.

    • Main Results:

    • A significant reduction in cigarette use prevalence was observed in intervention schools (8% vs. 18% at one-year follow-up).
    • Evidence for intervention effects on marijuana use was mixed.
    • No significant intervention effect was found for alcohol use.

    Conclusions:

    • The study successfully applied advanced statistical methods to analyze complex longitudinal intervention data.
    • The Midwestern Prevention Project demonstrated effectiveness in reducing adolescent cigarette smoking.
    • Further research may be needed to understand intervention effects on marijuana and alcohol use.