Related Experiment Video
Updated: Mar 13, 2026

Rigid Embedding of Fixed and Stained, Whole, Millimeter-Scale Specimens for Section-free 3D Histology by Micro-Computed Tomography
Published on: October 17, 2018
Technical Considerations for Red Marking Ink Use When Interpreting Specimen Radiographs: Case Report
Matthew E Brice1, Marisa Gossweiler1, Larry Bennett1
1From the Madigan Army Medical Center, 9040 Jackson Ave, Tacoma, WA 98431 (M.E.B., M.G.); and South Sound Imaging, Olympia, Wash (L.B.).
Abstract:
Artifacts are universal across all imaging modalities, varying in their conspicuity and significance. In this report three patients with pathology-proven breast cancer who had densities masquerading as microcalcifications at the resection margins of the lumpectomy specimens, but had negative microscopic margins, will be discussed. It was determined that these pseudocalcifications were the result of ink precipitates from a commonly utilized tissue marking dye. This artifact was further evaluated and reproduced by utilizing a boneless chicken breast as a phantom. © RSNA, 2016.
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