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Related Concept Videos

Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

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The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
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Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals. Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can be observed by an experiment: when the minerals of a bone are dissolved by soaking the bone in...
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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
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Bone tissue forms the internal skeleton of vertebrate animals, providing structure to the body.
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Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
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Bone Quality-Beyond Bone Mineral Density.

Thomas M Link1, Ursula Heilmeier1

  • 1Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California.

Seminars in Musculoskeletal Radiology
|October 15, 2016
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Summary
This summary is machine-generated.

Bone strength depends on both bone mass and quality. New technologies now allow for better measurement of bone quality, offering insights beyond bone mineral density for assessing skeletal health.

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Area of Science:

  • Orthopedics
  • Biomedical Engineering
  • Radiology

Background:

  • Bone strength is determined by both bone mass and bone quality.
  • Bone mineral density (BMD) quantifies bone mass, but bone quality assessment is more complex.
  • Bone quality encompasses architecture, texture, and mechanical properties.

Purpose of the Study:

  • To explain the importance of measuring bone quality.
  • To present various technologies for quantifying bone quality.
  • To review the strengths, weaknesses, and clinical feasibility of these technologies.

Main Methods:

  • Review of existing literature on bone quality assessment technologies.
  • Description of low-cost modalities: trabecular bone score (TBS) from DXA, quantitative ultrasound (QUS).
  • Description of advanced imaging modalities: MDCT, MRI, HR-pQCT.

Main Results:

  • Significant technological advancements have been made in measuring bone quality over the last decade.
  • Multiple modalities exist, ranging from low-cost to advanced imaging techniques.
  • Each technology presents unique advantages and limitations for clinical application.

Conclusions:

  • Accurate assessment of bone quality is crucial for a comprehensive understanding of bone strength.
  • A variety of emerging technologies offer improved methods for bone quality quantification.
  • Further evaluation of clinical utility and feasibility is needed for widespread adoption.