Rotavirus vaccination rate disparities seen among infants with acute gastroenteritis in Georgia

Area of Science:

• Pediatric Infectious Diseases
• Vaccinology
• Public Health

Background:

• Rotavirus (RV) is a leading cause of diarrheal disease in children under five.
• Rotavirus vaccination has significantly decreased disease burden in the United States.
• Understanding vaccination rate disparities is crucial for public health initiatives.

Purpose of the Study:

• To investigate potential disparities in rotavirus vaccination rates.
• To examine socio-economic differences influencing rotavirus vaccine uptake.
• To identify factors associated with incomplete rotavirus vaccination status.

Main Methods:

• Children with acute gastroenteritis were enrolled in the study.
• Rotavirus presence was confirmed using enzyme immunoassay.
• Vaccination records were reviewed to determine complete vs. incomplete RV doses.
• Logistic regression analysis was employed to assess disparities.

Main Results:

• No significant racial disparities (Black vs. white infants) in RV vaccination rates were found after controlling for covariates.
• Ethnicity, age at illness onset, birth year, and DTaP vaccination status were significant factors influencing RV vaccination status.
• Odds ratio for RV vaccination between Black and white infants was 1.15 (95% CI 0.74-1.78).

Conclusions:

• Racial and socio-economic factors do not appear to be primary determinants of rotavirus vaccination rates.
• Age and ethnicity significantly affect rotavirus vaccine status in children.
• Further research may explore the specific mechanisms by which age and ethnicity influence vaccination.