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Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
695
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

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Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
1.4K
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

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Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
868
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

506
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
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Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

793
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
793
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

359
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
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Related Experiment Video

Updated: Mar 13, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

Published on: August 28, 2018

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Coronary Artery Calcification.

Kazuhiro Osawa1, Rine Nakanishi1, Matthew Budoff1

  • 1Los Angeles Biomedical Research Institute at Harbor, University of California-Los Angeles, Los Angeles, CA, USA.

Global Heart
|October 16, 2016
PubMed
Summary

Coronary artery calcification (CAC) effectively stratifies cardiovascular risk in asymptomatic individuals. This marker helps identify those needing intervention, improving primary prevention strategies.

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Medical Imaging

Background:

  • Coronary artery calcification (CAC) is a key indicator of subclinical atherosclerosis.
  • CAC is an independent predictor of future coronary heart disease, especially in intermediate-risk, asymptomatic individuals.
  • CAC aids in reclassifying cardiovascular event risk.

Purpose of the Study:

  • To review the utility of CAC for cardiovascular disease risk stratification.
  • To describe the diagnostic value of CAC in identifying at-risk patients.
  • To present data from the Multi-Ethnic Study of Atherosclerosis (MESA) on CAC.

Main Methods:

  • Analysis of data from the MESA cohort study.
  • Evaluation of 6,814 asymptomatic men and women across 6 U.S. communities.

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  • Focus on CAC scoring for risk stratification.

    • Main Results:

    • CAC scoring demonstrated independent predictive power for major adverse cardiac events.
    • CAC is highly effective in stratifying cardiovascular risk.
    • The MESA study provides robust evidence for CAC's role in risk assessment.

    Conclusions:

    • CAC is a valuable tool for cardiovascular disease risk stratification in asymptomatic populations.
    • CAC scoring enhances the identification of individuals at risk for cardiac events.
    • The diagnostic value of CAC supports its integration into primary prevention strategies.