Related Experiment Video
Updated: Mar 13, 2026

05:46
Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
2.2K
Melanomalytic glaucoma secondary to iris melanoma
S Ajamil Rodanés1, C García-Álvarez1, M A Saornil Alvarez1
1Unidad de Tumores Intraoculares, Servicio de Oftalmología y Radioterapia, Hospital Clínico Universitario de Valladolid, Valladolid, España.
Archivos De La Sociedad Espanola De Oftalmologia
|October 18, 2016
Summary
A case of unilateral ocular hypertension revealed iris melanoma causing secondary glaucoma. Surgical resection and brachytherapy effectively managed this rare condition.
Area of Science:
- Ophthalmology
- Oncology
Background:
- Iris melanoma is a rare intraocular tumor.
- Unilateral glaucoma can be a presenting sign of ocular malignancy.
Observation:
- A 35-year-old male presented with unilateral ocular hypertension (40mmHg) in the right eye.
- Anterior segment examination revealed a melanotic lesion with extension into the anterior chamber angle.
Findings:
- Excisional biopsy confirmed iris melanoma.
- Secondary melanomalytic glaucoma was diagnosed.
- Adjuvant episcleral brachytherapy was administered.
Implications:
- Early diagnosis and multimodal treatment are crucial for managing iris melanoma and secondary glaucoma.
- Imaging studies are vital in cases of unilateral glaucoma with trabecular meshwork pigmentation.
Related Concept Videos
Glaucoma: Overview
1.6K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.6K
Angle Closure Glaucoma: Treatment
1.5K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.5K
Open Angle Glaucoma: Treatment
1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K

