Two fatal herpesvirus cases: Treatable but easily missed diagnoses
Christine Bookhout1, Vincent Moylan1, Leigh B Thorne1
1Department of Surgical Pathology, Women's and Children's Hospitals, The University of North Carolina at Chapel Hill, 3rd Floor, Room 30149, 101 Manning Drive, Chapel Hill, NC, 27514, USA.
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|October 18, 2016
Abstract:
Ill or immunosuppressed hospital patients are at increased risk for herpes simplex and herpes zoster virus infections, with high potential morbidity and mortality. Here, we present two cases of reactivation of herpes virus infections with delay in diagnosis, with ultimately fatal results. Since these infections are treatable, it is important to keep a high index of suspicion to facilitate early diagnosis and treatment.
Keywords:
ARDS, acute respiratory distress syndromeAutopsyBMT, bone marrow transplantCLL, chronic lymphocytic leukemiaCT, computed tomographyECMO, extracorporeal membrane oxygenationHSV, herpes simplex virusHerpes simplex virusImmunosuppressedPCR, polymerase chain reactionTEN, toxic epidermal necrolysisVZV, varicella zoster virusVaricella zoster virus

