IPMDS-Sponsored Scale Translation Program: Process, Format, and Clinimetric Testing Plan for the MDS-UPDRS and UDysRS

Area of Science:

• Neurology
• Movement Disorders
• Clinical Assessment

Background:

• Non-English translations of clinical scales are crucial for global research.
• Previous translations often lacked rigorous validation, hindering data comparability.
• The International Parkinson and Movement Disorder Society (MDS) initiated programs for validated translations of key scales.

Purpose of the Study:

• To present the methodology and results of clinimetric testing for non-English translations of MDS-sponsored scales.
• To detail the validation process for the MDS-UPDRS and UDysRS.
• To highlight the availability and progress of official translated versions.

Main Methods:

• A formal five-step translation and validation methodology was employed.
• Steps include registration, translation/back-translation, cognitive pretesting, field testing, and full clinimetric testing.
• This rigorous process ensures clarity, cultural appropriateness, and reliability of translated scales.

Main Results:

• 21 active language programs for the MDS-UPDRS, with 9 official translations completed.
• 19 active language programs for the UDysRS, with 3 official translations completed.
• This systematic approach yields validated translations, a rarity in neurology and movement disorders.

Conclusions:

• The MDS translation methodology provides a robust model for validating clinical scales in multiple languages.
• Validated translations are essential for ensuring homogeneity in multicenter research and clinical trials.
• This program facilitates global collaboration and data standardization in Parkinson's disease and movement disorder research.