Related Experiment Video
Updated: Mar 13, 2026

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations
Published on: January 10, 2015
Association between fire-safe cigarette legislation and residential fire deaths in the United States
Rebecca K Yau1, Stephen W Marshall2
1Injury Prevention Research Center, University of North Carolina at Chapel Hill, 137 East Franklin Street, Suite 500, Chapel Hill, NC, 27599-7505, USA. rebeccayau@unc.edu.
Background:
Cigarettes and other tobacco-related smoking products have traditionally been a major ignition source for residential fire deaths. In the United States, all 50 states and the District of Columbia have passed laws requiring that cigarettes self-extinguish if they are not being smoked (so-called fire-safe cigarette laws). The purpose of this study was to quantify the association between state-level implementation of fire-safe cigarette legislation and the rate of residential fire death.
Methods:
Poisson regression was used to analyze state-years data. Main intervention: Implementation dates for fire-safe cigarette legislation in each state.
Outcome:
Residential fire mortality rate.
Results:
Implementation of fire-safe cigarette legislation was associated with a 19% reduction in overall residential fire mortality rates, adjusted for demographic differences between states (rate ratio = 0.81, 95% confidence interval: 0.79, 0.84). This is approximately similar to the estimated proportion of residential fire deaths in which smoking materials are an ignition source (23%). Legislation implementation was associated with a protective effect for every age, sex, race, and ethnicity strata that we examined. State-specific residential fire mortality death rates decreased (defined as a drop of at least 5%) in 32 states after fire-safe cigarette legislation was implemented. In 12 states there was either less than a 5% decrease or an increase, and seven states had insufficient deaths to evaluate state-level changes.
Conclusions:
Implementation of fire-safe cigarette is associated with reductions in residential fire mortality rates.
Related Concept Videos
Statistical Methods for Analyzing Epidemiological Data
Hypothesis Test for Test of Independence
H0: The two variables (factors)...
Criteria for Causality: Bradford Hill Criteria - I
Criteria for Causality: Bradford Hill Criteria - II
Cause and Effect
Relative Risk

