Related Experiment Video
Updated: Mar 13, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
A Suspected Case of Silodosin-Induced Erythroderma
Annie Liu1,2, Lyne Giroux3
1Faculty of Medicine, The University of Toronto, Toronto, ON, Canada. msa.liu@mail.utoronto.ca.
Abstract:
An 86-year-old man developed a suspected severe erythroderma during treatment with silodosin (dosage unknown) for benign prostatic enlargement. Two weeks after starting silodosin, he developed a total-body scaling dermatitis. A biopsy was planned but the patient improved at his subsequent visit and it was not taken. Silodosin was discontinued and the patient received UVB phototherapy, clobetasol ointment, and several bland and protective skin-care measures. One week after the initial presentation, the patient demonstrated improvement in his total-body scaling. Based on these findings, the patient was diagnosed with a suspected silodosin-induced erythroderma. Due to limitations in the patient's clinical history and investigations, a Naranjo assessment score was not obtainable.
Related Concept Videos
Drug Toxicity: Allergic Reactions
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Transdermal Drug Delivery Systems
Hypersensitivity Reactions: Delayed Hypersensitivity Reactions
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Drug toxicity: Idiosyncratic Reactions

