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Updated: Mar 13, 2026

Surface Functionalization of Metal-Organic Frameworks for Improved Moisture Resistance
Published on: September 5, 2018
Furnishing Amine-Functionalized Metal-Organic Frameworks with the β-Amidoketone Group by Postsynthetic Modification
William J Gee1, Laura K Cadman1, Harina Amer Hamzah1
1Department of Chemistry, University of Bath , Claverton Down, Bath BA2 7AY, U.K.
Abstract:
Postsynthetic modification (PSM) of amino-functionalized metal-organic frameworks (MOFs) to those bearing pendant β-amidoketone arms using diketene is herein reported. Three unique MOF families demonstrate the scope of this transformation, which both is atom-economical and yields high conversions. In each case, the crystallinity was retained, and instances of exceptional solid-state ordering were observed in the PSM products, which has allowed detailed crystallographic characterization in multiple instances.
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