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Trends in Nonlipid Cardiovascular Disease Risk Factor Management in the Women's Interagency HIV Study and Association

David B Hanna1, Molly Jung1, Xiaonan Xue1

  • 11 Department of Epidemiology & Population Health, Albert Einstein College of Medicine , Bronx, New York.

AIDS Patient Care and Stds
|October 18, 2016
PubMed

Insights

Women with HIV show better hypertension and diabetes control than HIV-negative women, though many still don't meet target levels. Antiretroviral therapy adherence and virologic suppression are linked to improved cardiovascular disease risk factor management.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Cardiology

Background:

  • Cardiovascular disease (CVD) is a growing concern for women living with HIV.
  • Limited research exists on managing nonlipid CVD risk factors in this population.

Purpose of the Study:

  • To examine trends in hypertension, diabetes, and smoking cessation among women with and without HIV.
  • To assess the impact of antiretroviral therapy (ART) adherence and virologic suppression on CVD risk factors.

Main Methods:

  • Longitudinal analysis of data from the Women's Interagency HIV Study (2006-2014).
  • Poisson regression models to analyze time trends and differences between HIV-positive (HIV+) and HIV-negative (HIV-) women.
  • Evaluation of ART adherence and virologic suppression in HIV+ ART users.

Main Results:

  • HIV+ women had higher hypertension treatment (77% vs. 67%) and control (56% vs. 43%) than HIV- women, with improvements over time.
  • Diabetes treatment was similar, but control was better in HIV+ women (73% vs. 64%).
  • Smoking quit rates were similar between groups; virologic suppression correlated with better hypertension management.

Conclusions:

  • HIV+ women demonstrate superior control of hypertension and diabetes compared to HIV- women.
  • Despite improvements, a significant proportion of HIV+ women have not reached target levels for these CVD risk factors.
  • Effective management of HIV, including virologic suppression, positively impacts cardiovascular health.

Keywords:
HIV-1 viral loadantiretroviral therapycardiovascular diseasediabetes mellitushypertensionsmoking

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