Related Experiment Video
Updated: Aug 15, 2026

Experimental Protocol for Using Drosophila As an Invertebrate Model System for Toxicity Testing in the Laboratory
Published on: July 10, 2018
The effect of chronic lead intoxication in mature chickens
J Mazliah1, S Barron, E Bental
1Laboratory of Clinical Neurophysiology, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa.
Abstract:
In a study of chronic lead intoxication in mature chickens, blood lead levels were significantly lower in hens than in roosters receiving the same oral dose of lead. It was then shown that eggshells from lead-treated hens contained 6-12 times the lead concentration of eggshells from control hens. Similarly, the lead content of egg yolks from treated hens was significantly higher than yolks from controls. Lead-treated hens laid significantly more eggs during the period of observation of nearly 3 years because of the increased frequency of laying cycles, which was almost three times that of control hens. A further observation was histologic damage to the mature testes of the rooster.
Related Concept Videos
Toxicity Testing in Animals
Hepatic Encephalopathy

