Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Impact of Swept-Source OCT Angiographic Scanning Speeds on the Detection of Choriocapillaris Flow Deficits in Eyes With AMD.

Translational vision science & technology·2026

Same author

Author Correction: The STARD-AI reporting guideline for diagnostic accuracy studies using artificial intelligence.

Nature medicine·2026

Same author

Comparing Eye-Level and Site-Specific High-Risk OCT Biomarkers Preceding the Onset of Large Hypertransmission Defects.

American journal of ophthalmology·2026

Same author

Detection of Hyporeflective Core Drusen and the Onset of Large Choroidal Hypertransmission Defects in Intermediate AMD.

American journal of ophthalmology·2026

Same author

Development of a target product profile for artificial intelligence in diabetic eye screening in England: a modified Delphi consensus study.

The Lancet. Digital health·2026

Same author

Generative AI-enabled clinical decision support system in primary care: a pragmatic, cluster-randomized trial.

Nature medicine·2026

Search research articles

Related Experiment Video

Updated: Mar 13, 2026

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis

Published on: March 8, 2018

Punctate inner choroidopathy: A review.

Dana Ahnood¹, Savitha Madhusudhan², Marie D Tsaloumas³

¹Department of Ophthalmology, Royal Glamorgan Hospital, Cwm Taf University Health Board, Cardiff, United Kingdom.

Survey of Ophthalmology

|October 19, 2016

Summary

Punctate inner choroidopathy (PIC) is an inflammatory eye condition affecting young women. While potentially underdiagnosed, advanced imaging aids detection and tailored treatments, ranging from observation to immunosuppression, manage its variable impact on vision.

Keywords:

choroidal neovascularization posterior uveitis punctate inner choroidopathy white dot syndromes

More Related Videos

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

Related Experiment Videos

Last Updated: Mar 13, 2026

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis

Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis

Published on: March 8, 2018

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

Area of Science:

Ophthalmology
Inflammatory eye diseases
Chorioretinal disorders

Background:

Punctate inner choroidopathy (PIC) is an idiopathic inflammatory condition affecting the choroid and retina.
It predominantly impacts young, myopic women and is considered rare, with likely underdiagnosis.
The exact relationship between PIC and other white dot syndromes is not fully understood.

Purpose of the Study:

To explore the characteristics, diagnosis, and management of Punctate inner choroidopathy (PIC).
To discuss the potential spectrum of disease within the white dot syndromes, including PIC and multifocal choroiditis.
To highlight the role of advanced imaging in monitoring PIC and the variability in patient outcomes.

Main Methods:

Review of current literature and clinical understanding of Punctate inner choroidopathy.
Discussion of diagnostic advancements, particularly optical coherence tomography and autofluorescence imaging.
Analysis of treatment strategies, including observation, immunosuppression, and antiangiogenic therapies.

Main Results:

PIC's prevalence is uncertain, suggesting underdiagnosis.
PIC and multifocal choroiditis may represent a single disease spectrum influenced by host factors.
Patient outcomes vary significantly, from spontaneous recovery to severe vision loss.

Conclusions:

Punctate inner choroidopathy (PIC) presents a variable clinical course and visual impact.
Modern imaging techniques significantly improve the detection and monitoring of PIC.
Personalized treatment approaches are essential for managing this challenging inflammatory eye condition.