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Updated: Mar 13, 2026
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Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
Published on: November 4, 2015
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Congenital bronchopulmonary malformation: CT histopathological correlation
Martin Kyncl1, Martin Koci1, Lea Ptackova1
1Department of Radiology, 2nd Faculty of Medicine, Charles University in Prague and Faculty Hospital Motol, Prague, Czech Republic.
Summary
Postnatal computed tomography (CT) accurately identifies congenital bronchopulmonary malformations (BPMs) by showing high agreement with histology. This imaging is crucial for understanding BPMs and guiding treatment.
Area of Science:
- Radiology
- Pediatric Surgery
- Pathology
Background:
- Congenital bronchopulmonary malformations (BPMs) require accurate postnatal diagnosis.
- Histopathological analysis is the gold standard for BPM diagnosis.
Purpose of the Study:
- To evaluate the accuracy of postnatal computed tomography (CT) in identifying congenital bronchopulmonary malformations (BPMs).
- To compare CT findings with histopathological analysis for BPM diagnosis.
Main Methods:
- Retrospective analysis of CT scans from 24 patients with prenatally diagnosed BPMs and available histology.
- Blinded review of CT images by two radiologists using predetermined diagnostic criteria.
Main Results:
- 100% inter-radiologist agreement in CT diagnosis.
- 71% overlap between CT and histopathological diagnoses.
- Lesions predominantly located in lower lobes (75%).
- Type 2 congenital pulmonary airway malformation (CPAM) showed the least diagnostic agreement.
Conclusions:
- Contrast-enhanced chest CT is highly accurate in characterizing the spectrum of BPMs.
- CT provides essential information regarding BPM lesion type and structure.
- CT imaging aids in the diagnostic process for congenital lung abnormalities.
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