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Related Concept Videos

Pharmacovigilance01:19

Pharmacovigilance

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Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
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Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

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Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
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Biopharmaceutics and Pharmacokinetics: Overview01:28

Biopharmaceutics and Pharmacokinetics: Overview

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Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the...
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Drug Control Governance: Regulatory Bodies and Their Impact01:03

Drug Control Governance: Regulatory Bodies and Their Impact

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Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
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Drug Regulation01:25

Drug Regulation

3.2K
Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
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Pharmacogenetics of Drug Metabolism: Overview01:27

Pharmacogenetics of Drug Metabolism: Overview

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Genetic polymorphism in drug metabolism is crucial to the inter-individual variability observed in drug responses. Drug metabolism primarily involves the chemical modification of drugs and other xenobiotics to enhance their elimination by increasing their polarity. Two main classes of enzymes mediate this biotransformation process: Phase I enzymes, primarily cytochrome P450s, catalyze oxidation and reduction reactions, while other enzymes, such as esterases, mediate hydrolysis, and Phase II...
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Why do we need pharmacists in pharmacovigilance systems?

Hale Z. Toklu, Edward Mensah

    Online Journal of Public Health Informatics
    |October 19, 2016
    PubMed
    Summary

    Pharmacists play a vital role in medicine safety through pharmacovigilance. Utilizing electronic health records, they can detect adverse drug reactions early, improving patient outcomes and reducing healthcare costs.

    Keywords:
    adverse drug reaction reportinghealth systempharmacistpharmacotherapypharmacovigilancepharmacyrational use of medicine

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    Area of Science:

    • Pharmacovigilance
    • Drug Safety
    • Health Systems Pharmacy

    Background:

    • Pharmacovigilance is essential for monitoring pharmaceutical product safety.
    • Pharmacists are key healthcare professionals trained in rational and safe medicine use.
    • Optimizing pharmacist roles can enhance pharmacotherapy outcomes and reduce global health expenditures.

    Purpose of the Study:

    • To highlight the critical role of pharmacists in pharmacovigilance.
    • To explore how pharmacists can leverage electronic health records for drug safety.
    • To demonstrate the potential of pharmacists in early detection of adverse drug reactions.

    Main Methods:

    • Review of pharmacovigilance principles and practices.
    • Analysis of the pharmacist's expertise in drug management.
    • Examination of pharmacovigilance systems integrated with electronic health records.

    Main Results:

    • Pharmacists are uniquely positioned as drug experts to enhance pharmacovigilance.
    • Integration with electronic health records allows pharmacists to proactively monitor drug performance.
    • Early identification of adverse drug reactions by pharmacists leads to significant healthcare cost reductions.

    Conclusions:

    • Pharmacists are integral to effective pharmacovigilance systems.
    • Leveraging pharmacists' expertise with technology can improve medication safety.
    • Enhanced pharmacist involvement in pharmacovigilance contributes to better patient care and cost savings.