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Updated: Mar 13, 2026

Microfabrication of Implantable Optics Integrated in a Microstructured Imaging Window for Advanced In Vivo Imaging
Published on: April 11, 2025
Integrative optofluidic microcavity with tubular channels and coupled waveguides via two-photon polymerization
Yonglei Li1, Yangfu Fang2, Jiao Wang3
1Department of Materials Science & State Key Laboratory of ASIC and Systems, Fudan University, Shanghai 200433, China. yfm@fudan.edu.cn and Key Laboratory of Nanodevices and Applications, Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences, Suzhou 215125, China.
Abstract:
Miniaturization of functional devices and systems demands new design and fabrication approaches for lab-on-a-chip application and optical integrative systems. By using a direct laser writing (DLW) technique based on two-photon polymerization (TPP), a highly integrative optofluidic refractometer is fabricated and demonstrated based on tubular optical microcavities coupled with waveguides. Such tubular devices can support high quality factor (Q-factor) up to 3600 via fiber taper coupling. Microtubes with various diameters and wall thicknesses are constructed with optimized writing direction and conditions. Under a liquid-in-tube sensing configuration, a maximal sensitivity of 390 nm per refractive index unit (RIU) is achieved with subwavelength wall thickness (0.5 μm), which offers a detection limit of the devices in the order of 10-5 RIU. Such tubular microcavities with coupled waveguides underneath present excellent optofluidic sensing performance, which proves that TPP technology can integrate more functions or devices on a chip in one-step formation.
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