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Updated: Mar 13, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
Detection of left atrial dysfunction with speckle tracking echocardiography
A Bayramoğlu1, O Bektaş2, M Yaman2
1Department of Cardiology, Ordu University, Ordu, Turkey. adilbayramoglu@gmail.com.
Left atrial strain (LAs strain) and left ventricular end-diastolic pressure (LVEDP) independently predict SYNTAX scores. This relationship offers potential clinical utility for assessing coronary artery disease severity.
Area of Science:
- Cardiology
- Echocardiography
- Interventional Cardiology
Background:
- Assessing coronary artery disease severity is crucial.
- The SYNTAX score quantifies complexity but requires invasive methods.
- Non-invasive markers for predicting SYNTAX score are needed.
Purpose of the Study:
- To evaluate the relationship between the SYNTAX score and left ventricular end-diastolic pressure (LVEDP).
- To compare invasive LVEDP measurement with speckle-tracking echocardiography (STE) derived measures.
- To determine if STE-derived left atrial strain predicts SYNTAX score.
Main Methods:
- 124 patients undergoing cardiac catheterization were studied.
- SYNTAX scores were calculated and categorized.
- Left ventricular end-diastolic pressure (LVEDP) and left atrial strain (LAs strain, LAa strain) were measured invasively and via STE.
Main Results:
- Strong correlation found between SYNTAX score and LAs strain.
- Moderate correlations observed between SYNTAX score, LAa strain, and LVEDP.
- LAs strain and LVEDP were independent predictors of SYNTAX score in regression analysis.
Conclusions:
- Left atrial strain (LAs strain) and LVEDP are independent predictors of SYNTAX scores.
- STE-derived LAs strain shows promise as a non-invasive marker.
- These findings may enhance clinical assessment of coronary artery disease.
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