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[Current diagnostics and therapy recommendations for ocular basal cell carcinoma].
V Kakkassery1, K U Loeffler2, M Sand3,4
1Augenklinik - Universitätsklinikum Knappschaftskrankenhaus Bochum, Ruhr-Universität Bochum, In der Schornau 23-25, 44892, Bochum, Deutschland. vk@rub.de.
Summary
Novel treatments and guidelines enhance basal cell carcinoma (BCC) care. This review details ocular BCC features, diagnosis, and surgical and chemotherapeutic options, focusing on advanced cases.
Area of Science:
- Ophthalmology
- Dermatology
- Oncology
Background:
- Basal cell carcinoma (BCC) is a common skin cancer.
- Ocular and periocular BCC require specialized management.
- Recent advances include new chemotherapeutic drugs and updated guidelines.
Purpose of the Study:
- To provide a comprehensive overview of ocular BCC.
- To describe clinical signs, diagnostic tools, and histopathological subtypes.
- To review current and emerging therapeutic options for BCC.
Main Methods:
- Literature review of ocular BCC features and treatments.
- Emphasis on diagnostic criteria and histopathology.
- Discussion of surgical and chemotherapeutic approaches.
Main Results:
- Ocular BCC diagnosis relies on clinical signs and histopathology.
- Surgical resection with R0 margins is a key treatment.
- Novel chemotherapies offer new options for advanced BCC.
Conclusions:
- Comprehensive management of ocular BCC involves interdisciplinary collaboration.
- Early diagnosis and appropriate treatment are crucial.
- Advanced BCC cases benefit from tailored surgical and systemic therapies.
