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The effect of substituted aminoalkylaminoanthraquinones on eukaryotic cells
J Katzhendler1, G Bar-Ad, M Haran
1Department of Pharmaceutical Chemistry, Hebrew University School of Pharmacy, Jerusalem, Israel.
Drug Design and Delivery
|June 1, 1989
Abstract:
Nine aminoalkylaminoanthraquinones (I-IX) were evaluated for their cytotoxic potency against normal and malignant mammalian cells. The 1.8-di-(aminopropylamino) derivative (VIII) exhibited significant activity against several tumor cell systems and had some selectivity. The toxicity of this compound was also tested in growing chick embryos.