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Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

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Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
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Pleural Effusion I: Introduction01:25

Pleural Effusion I: Introduction

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Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
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Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

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A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
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Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

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Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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Transcellular Transport of Solutes01:23

Transcellular Transport of Solutes

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Transcellular transport of solutes is the movement of substances like monosaccharides and amino acids through polarized cells. This transport mechanism is primarily seen in epithelial and endothelial cells aided by membrane transport proteins such as channels and transporters. The tight junctions between these cells confine the membrane proteins to the two sides of the cell. The epithelial cells have distinct apical and basolateral domains. In contrast, the endothelial cells show the luminal...
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Aneurysm I: Introduction01:30

Aneurysm I: Introduction

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An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
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Extracorporeal Cardiopulmonary Resuscitation for Amniotic Fluid Embolism: Review and Case Report.

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Updated: Mar 13, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

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Amniotic Fluid Embolism.

Courtney Stanley Sundin1, Lauren Bradham Mazac

  • 1Courtney Stanley Sundin is a Clinical Nurse Supervisor at Labor & Delivery, Baylor Scott & White All Saints Medical Center, Andrews Women's Hospital, Fort Worth, TX. The author can be reached via e-mail at courtneysundin@gmail.com Lauren Bradham Mazac is a Clinical Nurse Supervisor at Labor & Delivery, Baylor Scott & White All Saints Medical Center, Andrews Women's Hospital, Fort Worth, TX.

MCN. the American Journal of Maternal Child Nursing
|October 19, 2016
PubMed
Summary
This summary is machine-generated.

Amniotic fluid embolism (AFE) is a rare, unpredictable pregnancy complication. Prompt recognition and multidisciplinary treatment, including transfusion protocols, are crucial for improving maternal outcomes.

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Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Critical Care in Pregnancy

Background:

  • Amniotic fluid embolism (AFE) is a rare, unpredictable, and often fatal obstetric emergency.
  • AFE typically presents during labor or the immediate postpartum period with abrupt cardiorespiratory collapse.
  • The pathophysiology involves an aberrant maternal response to fetal material entering circulation.

Purpose of the Study:

  • To highlight the critical need for rapid recognition and management of Amniotic Fluid Embolism.
  • To emphasize the diagnostic challenges due to the absence of specific criteria or tests.
  • To underscore the importance of a multidisciplinary approach and preparedness for AFE.

Main Methods:

  • Clinical diagnosis based on the triad of hypoxia, hypotension, and coagulopathy.
  • Exclusion of other plausible causes for the clinical presentation.
  • Case study illustrating a rapid AFE complication during an otherwise normal obstetric course.

Main Results:

  • The case demonstrates the sudden and severe nature of AFE, even in low-risk pregnancies.
  • Timely intervention is paramount to mitigate severe maternal morbidity and mortality.
  • Preparedness through knowledge and simulation of emergency protocols is essential.

Conclusions:

  • Early identification and swift, coordinated management are key to improving AFE outcomes.
  • Multidisciplinary team training and familiarity with Massive Obstetric Transfusion protocols enhance response efficacy.
  • While unpreventable, effective management strategies can significantly reduce AFE-related mortality.