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Related Concept Videos

Cranial Bones: Superior and Posterior View01:14

Cranial Bones: Superior and Posterior View

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The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
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Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
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Primary Frontoparietal Osteosarcoma.

Kuauhyama Luna-Ortiz1, Mario Alonso-Calamaco, Ramses U Ortiz-Leyva

  • 1*Department of Head and Neck Surgery †Department of Neuroscience, Instituto Nacional de Cancerologia, Mexico City ‡Deparment of Surgery (Head & Neck), Hospital General Manuel Gea Gonzalez, Mexico CDMX, Mexico.

The Journal of Craniofacial Surgery
|October 19, 2016
PubMed
Summary

Craniofacial osteosarcoma, a rare bone cancer, presented as a rapidly growing tumor in a 43-year-old female. Surgical resection was successful, with the patient undergoing follow-up.

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Area of Science:

  • Oncology
  • Neurosurgery
  • Head and Neck Surgery

Background:

  • Osteosarcoma is a rare malignancy, particularly in the craniofacial region.
  • Early detection and prompt surgical intervention are crucial for managing bone tumors.

Observation:

  • A 43-year-old female presented with a self-detected right frontoparietal tumor.
  • The tumor rapidly increased in size from 3 cm to 8x9 cm over a 6-month period.
  • Surgical delay was attributed to two episodes of upper respiratory tract infection.

Findings:

  • A large craniofacial osteosarcoma involving the dura mater and orbital roof was surgically resected.
  • Surgical procedures included craniotomy, dural plasty, methylmethacrylate plate insertion, and anterolateral thigh flap reconstruction.
  • No adjuvant therapy was administered post-operatively.

Implications:

  • This case highlights the aggressive nature of craniofacial osteosarcoma and the importance of timely surgical management.
  • Multidisciplinary surgical approaches are essential for successful tumor resection and reconstruction.
  • Further research into optimal adjuvant therapies for craniofacial osteosarcoma is warranted.