Visualizing the nanoscale: protein internal dynamics and neutron spin echo spectroscopy
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Updated: Mar 13, 2026

Study of Protein Dynamics via Neutron Spin Echo Spectroscopy
Published on: April 13, 2022
1Department of Chemistry and Biochemistry, City College of New York, PhD Programs in Chemistry and Biochemistry, CUNY, United States.
Abstract:
The most complex molecular machines are proteins found within cells. Protein dynamics, in particular dynamics on nanoscales, presents us with a novel paradigm for cell signaling: the idea that proteins and protein complexes can communicate directly within themselves to effect long-range information transfer, via coupled domains and correlated residue clusters. This idea has been little explored, in large part because of a paucity of experimental techniques that can address the necessary questions. Here we review recent progress in developing a promising new approach, neutron spin echo spectroscopy.
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