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An outbreak investigation of congenital rubella syndrome in Solomon Islands, 2013
Kara N Durski1, Carol Tituli2, Divi Ogaoga3
1WHO Headquarters, Geneva, Switzerland .
Insights
A rubella outbreak in the Solomon Islands led to a congenital rubella syndrome (CRS) investigation. The study identified 13 CRS cases, highlighting the need for rubella vaccination to prevent severe outcomes.
Area of Science:
- Public Health
- Epidemiology
- Infectious Disease Surveillance
Background:
- A rubella outbreak occurred in the Solomon Islands in May 2012.
- A suspected case of congenital rubella syndrome (CRS) was reported in 2013, prompting an investigation.
Purpose of the Study:
- To investigate suspected cases of congenital rubella syndrome (CRS) following a rubella outbreak.
- To describe the findings and implemented measures for CRS cases.
Main Methods:
- Prospective CRS surveillance was conducted from April to July 2013.
- Retrospective case finding reviewed medical records for cases born between January and March 2013.
- Established World Health Organization case definitions were used to identify CRS cases.
Main Results:
- A total of 13 CRS cases were identified: 2 laboratory-confirmed, 4 clinically confirmed, and 7 suspected.
- Five additional cases were identified retrospectively.
- Mothers' ages ranged from 20 to 36 years, with three recalling rash illness in early pregnancy.
Conclusions:
- Further CRS cases may exist beyond this investigation.
- Managing CRS cases presents challenges in resource-limited settings.
- Rubella vaccination is crucial for preventing CRS and its severe consequences.
Introduction:
During May 2012, a rubella outbreak was declared in Solomon Islands. A suspected case of congenital rubella syndrome (CRS) was reported from one hospital 11 months later in 2013. This report describes the subsequent CRS investigation, findings and measures implemented.
Methods:
Prospective CRS surveillance was conducted at the newborn nursery, paediatric and post-natal wards, and the paediatric cardiology and ophthalmology clinics of the study hospital from April to July 2013. Retrospective case finding by reviewing medical records was also undertaken to identify additional cases born between January and March 2013 for the same wards and clinics. Cases were identified using established World Health Organization case definitions for CRS.
Results:
A total of 13 CRS cases were identified, including two laboratory-confirmed, four clinically confirmed and seven suspected cases. Five CRS cases were retrospectively identified, including four suspected and one clinically confirmed case. There was no geospatial clustering of residences. The mothers of the cases were aged between 20 and 36 years. Three of the six mothers available for interview recalled an acute illness with rash during the first trimester of pregnancy.
Discussion:
Additional CRS cases not captured in this investigation are likely. Caring for CRS cases is a challenge in resource-poor settings. Rubella vaccination is safe and effective and can prevent the serious consequences of CRS. Well planned and funded vaccination activities can prevent future CRS cases.
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