Caustic Ingestion in Children: a Systematic Review and Meta-Analysis

Mandana Rafeey1, Morteza Ghojazadeh2, Saeede Sheikhi3

  • 1Department of Pediatrics Gastroenterology, Medicine Faculty, Liver & Gastrointestinal Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Insights

Accidental caustic ingestion is a common pediatric issue, often involving household cleaners. This preventable problem requires coordinated efforts from families, health professionals, and media for effective management and prevention.

Area of Science:

  • Pediatric Toxicology
  • Public Health
  • Gastroenterology

Background:

  • Accidental caustic ingestion is a significant health concern in children.
  • Household cleaning products are frequently involved in these incidents.

Purpose of the Study:

  • To systematically review the literature on pediatric caustic ingestion.
  • To identify common substances, risk factors, and outcomes associated with caustic ingestion in children.

Main Methods:

  • Systematic review of articles from Science Direct, ProQuest, Google Scholar, and PubMed.
  • Keywords: caustic, corrosive, ingestion, children. Limited to English and Persian articles.
  • Data analysis using Comprehensive Meta-Analysis2 and PASW Statistics 18.

Main Results:

  • Analyzed 64 articles with 11,345 cases of pediatric caustic ingestion.
  • Higher incidence observed in young boys; common agents include household cleaners (bleaches, cleaners).
  • Reported complications include esophageal cancer, death, and digestive/respiratory issues; diagnosis and treatment are often invasive and costly.

Conclusions:

  • Pediatric caustic ingestion is a serious but preventable and manageable issue.
  • Multifaceted efforts involving families, government, industry, healthcare teams, and media are crucial for adequate management and prevention.

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