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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
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Community-based study on elderly CKD subjects and the associated risk factors
Yan-Ping Huang1, Tao Zheng2,3, Dan-Huan Zhang1
1a Department of Nephrology , Tongren Hospital Shanghai Jiao Tong University School of Medicine , Shanghai , China.
Renal Failure
|October 21, 2016
Summary
Chronic kidney disease (CKD) affects 16.4% of elderly Shanghai residents, with higher prevalence in females. Key risk factors include age, female sex, hypertension, and hypercholesterolemia.
Area of Science:
- Gerontology
- Nephrology
- Public Health
Background:
- Chronic kidney disease (CKD) is a significant public health concern, particularly in aging populations.
- Early detection and management of CKD are crucial for improving health outcomes in the elderly.
Purpose of the Study:
- To determine the prevalence of CKD in community-dwelling elderly individuals in Shanghai, China.
- To identify demographic and clinical risk factors associated with CKD in this population.
Main Methods:
- A cross-sectional study involving 24,886 residents aged 65 and older in Shanghai's Changning District.
- Renal function was assessed using the CKD-EPI equation to estimate glomerular filtration rate (eGFR).
- Statistical analyses examined associations between participant characteristics and CKD indicators.
Main Results:
- The prevalence of CKD was 16.4% among the elderly participants (mean age 74.9 years).
- Females exhibited a higher CKD prevalence (17.6%) than males (14.9%).
- Significant risk factors for CKD included older age, female sex, hyperuricemia, hypertension, cardiovascular disease, hypercholesterolemia, and smoking.
Conclusions:
- CKD prevalence is notably high in Shanghai's elderly population.
- Risk factors for CKD in the elderly largely mirror those in the adult population.
- Hypercholesterolemia emerged as a distinct risk factor for CKD specifically in the elderly cohort.
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