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Related Concept Videos

Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

841
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
841
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

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Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
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Deglutition01:25

Deglutition

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Swallowing, otherwise known as deglutition, facilitates the transport of food from the mouth to the stomach. It is a multifaceted process that involves both the tongue and the muscles of the throat and esophagus. Saliva and mucus aid in this process, which takes approximately 4 to 8 seconds for semi-solid or solid food and around 1 second for liquids or very soft food.
Swallowing can be divided into three stages: the voluntary phase, the pharyngeal phase, and the esophageal phase. Although the...
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Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

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Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
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Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

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Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
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Upper GI Series: Barium Swallow01:24

Upper GI Series: Barium Swallow

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The Barium Swallow Study, or a Barium Esophagogram, is a diagnostic imaging method used to visualize the upper gastrointestinal (GI) tract, including the esophagus, stomach, and small intestine. It employs barium sulfate, a radiopaque contrast material, to provide clear images of the upper digestive system, helping to identify abnormalities, diseases, or structural issues.
Purpose and Procedure
Patients undergoing this procedure ingest a liquid containing barium sulfate with a chalky...
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Related Experiment Video

Updated: Mar 13, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
08:32

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

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[Dysphagia in children].

E Ten Velde1, B C Gonera-de Jong

  • 1Medisch Spectrum Twente., afd. Kindergeneeskunde, Enschede.

Nederlands Tijdschrift Voor Geneeskunde
|October 21, 2016
PubMed
Summary

Pediatric dysphagia can stem from various causes, including esophageal achalasia and eosinophilic esophagitis. Promptly diagnosing and treating underlying somatic disorders is crucial for effective management in children.

Area of Science:

  • Pediatric Gastroenterology
  • Clinical Case Reports

Background:

  • Dysphagia in children presents a diagnostic challenge, often requiring differentiation between functional, anatomical, and psychogenic causes.
  • Esophageal impaction of solid food is a significant symptom warranting thorough investigation.

Observation:

  • Case 1: A 16-year-old boy with long-standing dysphagia, initially suspected to be psychogenic, was diagnosed with esophageal achalasia.
  • Case 2: A 15-year-old girl presented with distal esophageal food impaction and was diagnosed with eosinophilic esophagitis.

Findings:

  • Esophageal achalasia required repeated balloon dilatation for symptom management in the first case.
  • Eosinophilic esophagitis in the second case responded well to acid suppression and budesonide treatment, achieving remission.

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Last Updated: Mar 13, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
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Implications:

  • Highlights the diverse etiology of pediatric dysphagia, emphasizing the need to exclude organic conditions before considering psychogenic factors.
  • Underscores the importance of recognizing 'red flag' symptoms like weight loss in pediatric dysphagia evaluations.