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Related Concept Videos

Assessing Body Temperature - Temporal Artery01:19

Assessing Body Temperature - Temporal Artery

1.5K
Here is a stepwise guide to assessing the body temperature at the temporal artery using a temporal artery thermometer
Step 1: Perform hand hygiene and don a fresh pair of gloves to prevent cross-infection and ensure patient safety.
Step 2: Explain the procedure to the patient to establish trust. Clear communication establishes trust with the patient, ensures they understand what to expect, promotes cooperation, and enhances comfort during the procedure.  
Step 3: Assess the patient's...
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Increased Body Temperature01:25

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A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
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Related Experiment Video

Updated: Mar 13, 2026

Non-thermal Infrared Light Treatment of Ischemia/Reperfusion Injury and Subsequent Analysis of Macrophage Differentiation
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Body Temperature Modulates Infarction Growth following Endovascular Reperfusion.

S Dehkharghani1,2, M Bowen3, D C Haussen2

  • 1From the Department of Radiology and Imaging Sciences (S.D., M.B., T.G., A.P.), Emory University Hospital, Atlanta, Georgia Seena.Dehkharghani@NYUMC.Org.

AJNR. American Journal of Neuroradiology
|October 21, 2016
PubMed
Summary
This summary is machine-generated.

Fever in acute ischemic stroke patients receiving reperfusion therapy increases infarct growth and is associated with worse clinical outcomes. This highlights the importance of temperature management in stroke care.

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Area of Science:

  • Neurology
  • Neuroscience
  • Medical Imaging

Background:

  • Neuronal tissue is sensitive to temperature changes.
  • The effect of fever on the ischemic penumbra after reperfusion is not well understood.
  • Acute ischemic stroke management often involves reperfusion therapies.

Purpose of the Study:

  • To investigate the impact of fever on infarct growth and clinical outcomes in successfully reperfused acute ischemic stroke patients.
  • To determine if elevated body temperature influences the expansion of the ischemic penumbra despite successful reperfusion.

Main Methods:

  • Analysis of 129 successfully reperfused acute ischemic stroke patients within 12 hours of onset.
  • CT perfusion imaging to assess infarct core, hypoperfusion, and penumbral mismatch volumes.
  • Correlation and logistic regression analyses to evaluate the association between fever (>37.5°C) and infarction growth/clinical outcomes (90-day mRS ≤2), controlling for covariates.

Main Results:

  • A significant correlation was found between fever and increased relative infarction growth (Kendall τ = 0.24, P = .002).
  • Fever showed a trend towards predicting unfavorable clinical outcomes (90-day mRS >2) (OR = 0.31, P = .05).
  • An optimized predictive model for favorable outcomes included age, NIHSS score, reperfusion time, and fever.

Conclusions:

  • Systemic temperature elevation, specifically fever, promotes infarction growth even after successful reperfusion in acute ischemic stroke.
  • Fever negatively impacts clinical outcomes in stroke patients.
  • Temperature management should be considered in acute ischemic stroke treatment protocols.