Related Experiment Video
Updated: Mar 13, 2026
06:21
Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer
Published on: May 10, 2024
1.4K
Pernicious Anaemia with Gastric Carcinoids.
Shaik Jani Basha1, N R Shetty2, Harshad Devarbhavi3
1Resident.
The Journal of the Association of Physicians of India
|October 21, 2016
Summary
This case study highlights a rare simultaneous diagnosis of pernicious anemia and gastric carcinoids in a 42-year-old male. It underscores the importance of esophago-gastric-duodenoscopy for pernicious anemia patients.
Area of Science:
- Gastroenterology
- Hematology
- Oncology
Background:
- Pernicious anemia is an autoimmune condition causing vitamin B12 deficiency.
- Beta thalassemia trait is a genetic blood disorder.
- Gastric carcinoids are neuroendocrine tumors of the stomach.
Observation:
- A 42-year-old male presented with chronic anemia.
- Diagnostic workup revealed pernicious anemia and beta thalassemia trait.
- Esophago-gastric-duodenoscopy identified gastric carcinoids and gastric atrophy.
Findings:
- The patient had a rare co-occurrence of pernicious anemia and gastric carcinoids.
- Gastric atrophy was also noted in conjunction with these conditions.
Implications:
- This case emphasizes the diagnostic value of esophago-gastric-duodenoscopy in patients with pernicious anemia.
- Simultaneous occurrence of these conditions necessitates thorough gastrointestinal evaluation.
- Highlights potential links between autoimmune gastritis and gastric neuroendocrine tumors.
Related Concept Videos
01:17Gastritis-II: Pathophysiology
1.7K
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
1.7K
01:27Gastritis-I: Introduction and Types
3.0K
Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
3.0K
01:23Gastritis III: Clinical Manifestations and Management
1.6K
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
1.6K
01:30Peptic Ulcer Disease I: Introduction
981
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
981
01:25Peptic Ulcer Disease V: Surgical Management and Nursing Care
1.1K
Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
Surgical Interventions for Peptic Ulcer Disease
1.1K
01:22Pathophysiology of Peptic Ulcer Disease: Injurious Factors
1.4K
Peptic ulcers are sores on the stomach's inner lining and the upper small intestine, which are the result of disruptions in the mucosal layer that houses parietal cells which produce gastric acid, and chief cells which secrete pepsinogen.
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
1.4K