Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hyponatraemia and clomipramine therapy.

D R Pledger1, H Mathew

  • 1Staincliffe General Hospital, Dewsbury, West Yorkshire.

The British Journal of Psychiatry : the Journal of Mental Science
|February 1, 1989
PubMed
Summary

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) was unexpectedly found in a patient on clomipramine. This case highlights a potential adverse drug reaction requiring clinical awareness.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ischaemic conditioning strategies reduce ischaemia/reperfusion-induced organ injury.

British journal of anaesthesia·2014
Same author

Introduction of automatically generated comment in clinical biochemistry: an audit of technical effectiveness.

British journal of biomedical science·2008
Same author

Implications of different DCCT-aligned HbA1c methods on GMS clinical indicators.

Diabetic medicine : a journal of the British Diabetic Association·2008
Same author

Different DCCT-aligned HbA1c methods and the GMS contract.

International journal of clinical practice·2008
Same author

HDL-cholesterol and triglycerides: an overlooked issue?

Journal of clinical pathology·2007
Same author

Rapid thyrotoxicosis in anaplastic thyroid carcinoma.

The Journal of laryngology and otology·2006

Area of Science:

  • Endocrinology
  • Pharmacology
  • Nephrology

Background:

  • Clomipramine is a tricyclic antidepressant.
  • SIADH is a condition characterized by excessive antidiuretic hormone release.
  • Antidepressant-induced SIADH is a recognized but uncommon adverse effect.

Observation:

  • A patient undergoing clomipramine therapy was incidentally diagnosed with SIADH.
  • The detection was fortuitous, suggesting it may be underdiagnosed.

Findings:

  • Clomipramine therapy was associated with the development of SIADH.
  • This association underscores the importance of monitoring electrolyte balance in patients treated with this medication.

Implications:

  • Clinicians should consider SIADH in patients on clomipramine presenting with hyponatremia.
  • Further investigation into the mechanisms of clomipramine-induced SIADH may be warranted.
  • This case contributes to the understanding of drug-induced SIADH and its management.

Related Experiment Videos