Related Experiment Video
Updated: Mar 13, 2026

07:35
In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility
Published on: April 21, 2022
2.7K
Changes in Retinal Thickness after Vitrectomy for Epiretinal Membrane with and without Internal Limiting Membrane
Shumpei Obata1, Masato Fujikawa, Keisuke Iwasaki
1Department of Ophthalmology, Shiga University of Medical Science, Otsu, Japan.
Ophthalmic Research
|October 21, 2016
Summary
Vitrectomy for epiretinal membranes (ERMs) impacts visual acuity and retinal thickness. Internal limiting membrane (ILM) peeling during vitrectomy may reduce ERM recurrence without affecting these outcomes.
Area of Science:
- Ophthalmology
- Retinal Surgery
Background:
- Idiopathic epiretinal membranes (ERMs) can cause visual distortion.
- Vitrectomy is a surgical procedure to remove ERMs.
Purpose of the Study:
- To compare anatomic and functional changes after vitrectomy for ERMs.
- To evaluate the impact of internal limiting membrane (ILM) peeling on these outcomes.
Main Methods:
- Retrospective review of 100 eyes undergoing vitrectomy for ERM.
- Optical coherence tomography (OCT) measured retinal thickness (RT) in 9 zones.
- Comparison of best-corrected visual acuity (BCVA) and RT between groups with and without ILM peeling.
Main Results:
- No significant differences in BCVA or RT between groups at 12 months postoperatively.
- ERM recurrence was significantly lower in the ILM peeling group (20.5%) compared to the no-ILM peeling group (42.6%).
Conclusions:
- Vitrectomy for ERM improves BCVA and RT, but ILM peeling does not further enhance these.
- ILM peeling may be associated with a reduced rate of ERM recurrence.

