[Clinical analysis of bone diseases in patients under chronic hemopurification]

In this article are summed up the x-ray changes of bones, laboratory data and clinical manifestations of 62 patients treated by hemodialysis (HD), hemofiltration (HF) and HD plus HF alternately from 1978 to 1987.

The incidence of bone disease reached 79% without significant difference between the three groups. The values of serum calcium, phosphate, alkaline phosphatase and carbon dioxide combining power (CO2CP) in these three groups were obviously abnormal. Three cases of bone necropsy showed aluminium deposits in bone tissues. We insist that to prevent the occurrence and worsening of bone disease during chronic hemopurification, reverse osmosis water should be used to prepare dialysates and substitution fluids. It is not advisable to use aluminum containing phosphate binder. The use of active VitD3 in the early stage, modulation of calcium content in dialysates, control of the intake of phosphates from foods, and giving desferrioxamine intravenously when necessary are helpful.