Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nursing Implementation01:15

Nursing Implementation

6.5K
Implementation is the execution of the nursing care plan developed during the planning phase.
The five steps to implementing effective nursing care include reassessing the patient, reviewing and revising the existing nursing care plan, organizing the resources and care delivery, anticipating and preventing complications, and implementing nursing interventions.
6.5K
Preclinical Development: Overview01:28

Preclinical Development: Overview

6.3K
Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
6.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sustaining progress in HIV care in Africa with a transition to enabled self-care: a modelling study.

The Lancet. Global health·2026
Same author

Sexual Behaviors and Psychosocial Health Among Men Who Have Sex with Men with and without Female Partners in Kenya: Baseline Findings from the Tatu Pamoja Study.

Journal of sex research·2026
Same author

HIV prevention must incorporate acute HIV infection screening.

The lancet. HIV·2026
Same author

Economic barriers to diagnostic equity: A multi-country analysis of patient costs for rapid SARS-CoV-2 testing in sub-Saharan Africa.

PloS one·2026
Same author

Development of a modular neonatal neurological examination: from a short screening test to a detailed assessment of specific aspects of neurological function.

European journal of pediatrics·2026
Same author

Investigation of Correlates of Protection Against Gonococcal Infection by Comparative Immunoprofiling of Responses in Experimental and Clinical Studies.

The Journal of infectious diseases·2026

Related Experiment Video

Updated: Mar 13, 2026

Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy NIRS Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa
08:10

Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy NIRS Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa

Published on: February 2, 2018

15.7K

PrEP implementation research in Africa: what is new?

Frances M Cowan1,2, Sinead Delany-Moretlwe3, Eduard J Sanders4,5

  • 1Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK.

Journal of the International AIDS Society
|October 21, 2016
PubMed
Summary

Pre-exposure prophylaxis (PrEP) is effective for HIV prevention in Africa, but successful implementation requires addressing demand, supply, and adherence challenges. Key populations and adolescent girls need tailored strategies for PrEP delivery and support across the continent.

Keywords:
AfricaHIV/AIDSadherenceempowermentimplementationkey populationspre-exposure prophylaxisprevention

More Related Videos

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
23:56

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

17.4K
A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

13.7K

Related Experiment Videos

Last Updated: Mar 13, 2026

Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy NIRS Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa
08:10

Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy NIRS Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa

Published on: February 2, 2018

15.7K
Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
23:56

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

17.4K
A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

13.7K

Area of Science:

  • Public Health
  • Epidemiology
  • HIV Prevention

Background:

  • Sub-Saharan Africa bears a significant burden of new HIV infections, with millions eligible for pre-exposure prophylaxis (PrEP).
  • Key populations and adolescent girls and young women (AGYW) are at substantial risk and stand to benefit from PrEP.
  • Despite proven efficacy, significant implementation questions remain for rolling out PrEP across Africa.

Purpose of the Study:

  • To identify and summarize critical implementation questions for pre-exposure prophylaxis (PrEP) in Africa.
  • To highlight overarching issues in PrEP delivery, including demand creation, supply-side challenges, and adherence support.
  • To inform the effective rollout of PrEP programs across diverse populations and settings in Africa.

Main Methods:

  • The study synthesizes existing knowledge and identifies key implementation challenges based on the current understanding of PrEP efficacy and rollout in Africa.
  • It reviews the needs of various populations, including individuals in sero-discordant relationships, key populations (sex workers, MSM, transgender women, IDUs), and AGYW.
  • The analysis focuses on overarching issues critical for successful PrEP implementation: demand, supply, and adherence.

Main Results:

  • Creating demand for PrEP necessitates normalizing HIV prevention and empowering high-risk individuals.
  • Ensuring accessible and integrated services is crucial for PrEP supply, addressing stigma and co-occurring health needs.
  • Effective adherence support must consider social and structural factors, combining self-efficacy interventions with individualized support.

Conclusions:

  • The efficacy of tenofovir-based PrEP is established, but successful implementation hinges on addressing practical challenges.
  • Addressing demand, supply, and adherence through tailored, community-centered strategies is essential for PrEP scale-up in Africa.
  • Further assessment of implementation questions is vital for optimizing PrEP's impact on the HIV epidemic in Africa.