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Two Methods for Establishing Primary Human Endometrial Stromal Cells from Hysterectomy Specimens
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Endometrial stromal sarcoma: An aggressive uterine malignancy
Chaitra P Adiga1, Manju Gyanchandani1, Lakshmikantha N Goolahally1
1Department of Radiology, Sagar hospitals, Jayanagar, Bangalore, India.
Journal of Radiology Case Reports
|October 21, 2016
Summary
Endometrial stromal sarcoma (ESS) is a rare uterine cancer. This case highlights MRI
Area of Science:
- Gynecologic Oncology
- Radiology
- Pathology
Background:
- Endometrial stromal sarcoma (ESS) is an aggressive uterine malignancy.
- Accurate diagnosis and staging are crucial for patient management.
Observation:
- A 42-year-old nulliparous woman with chronic kidney disease presented with acute urinary retention and vaginal bleeding.
- Imaging revealed a large, heterogeneous endometrial mass with internal vascularity.
- MRI demonstrated a lobulated mass extending into the vagina with characteristic T2-weighted findings.
Findings:
- Magnetic resonance imaging (MRI) effectively characterized the large endometrial stromal sarcoma.
- Specific MRI features, including linear hypointense bands on T2-weighted images, were indicative of ESS.
- MRI aided in assessing local mass effect and staging the tumor.
Implications:
- Distinguishing ESS from benign conditions and other uterine malignancies is vital for optimal treatment.
- MRI is a valuable tool for diagnosing and staging endometrial stromal sarcoma.
- This case underscores the importance of advanced imaging in managing rare gynecologic cancers.
