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Relationship between thyroid stimulating hormone and night shift work.

So-Hyun Moon1, Bum-Joon Lee2, Seong-Jin Kim1

  • 1Department of Occupational and Environmental Medicine, Inha University Hospital, Incheon, Republic of Korea ; Department of Social and Preventive Medicine, School of Medicine, Inha University, Incheon, Republic of Korea.

Annals of Occupational and Environmental Medicine
|October 21, 2016
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Summary
This summary is machine-generated.

Night shift work is linked to higher thyroid stimulating hormone (TSH) levels and an increased risk of subclinical hypothyroidism in female hospital workers. This highlights potential thyroid health concerns for night shift professionals.

Keywords:
Night shiftSubclinical hypothyroidismThyroid stimulating hormone

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Area of Science:

  • Endocrinology
  • Occupational Health

Background:

  • Night shift work is associated with adverse health outcomes.
  • Limited research exists on the link between night shift work and thyroid diseases.
  • Thyroid stimulating hormone (TSH) levels are a key indicator of thyroid function.

Purpose of the Study:

  • To investigate the relationship between night shift work and thyroid stimulating hormone (TSH) levels.
  • To examine changes in TSH levels over time in relation to night shift work.
  • To assess the risk of subclinical hypothyroidism among night shift workers.

Main Methods:

  • Utilized medical check-up data from 967 female hospital workers (2011-2015).
  • Analyzed thyroid stimulating hormone (TSH) levels using general linear models (GLM).
  • Employed generalized estimating equations (GEE) for longitudinal analysis of repeated measurements.

Main Results:

  • Night shift workers showed significantly higher TSH levels (0.303 mIU/L) compared to non-night shift workers (p=0.006).
  • Night shift workers had a 1.399-fold increased risk of subclinical hypothyroidism (p=0.022).
  • Adjustments were made for age and department in the analyses.

Conclusions:

  • Night shift work may increase the risk of developing thyroid diseases.
  • Findings suggest a need for monitoring thyroid health in night shift workers.
  • Further research is warranted to understand the mechanisms linking night shift work and thyroid dysfunction.