Immunohistochemical expression of vascular endothelial growth factor in orofacial lesions - A review
Bhavana Gupta1, Shaleen Chandra2, Vineet Raj3
1Senior Lecturer, Department of Oral Pathology, Rama Dental College, Kanpur, U.P., India.
Journal of Oral Biology and Craniofacial Research
|October 21, 2016
Abstract:
Angiogenesis is considered to be an important biological process in disease progression and tumorigenesis. Among the various factors associated with angiogenesis, vascular endothelial growth factor (VEGF) is a leading candidate. VEGF induces the proliferation, differentiation, and migration of vascular endothelial cells, increases capillary permeability, and enhances endothelial cell survival by preventing apoptosis. This article reviews and highlights the role of VEGF in health, and various oral diseases.


