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Data on correlation between CT-derived and MRI-derived myocardial extracellular volume
Yoshie Kurita1, Kakuya Kitagawa1, Yusuke Kurobe1
1Department of Radiology and Mie University Hospital, Tsu, Japan.
This study explores cardiac CT for measuring myocardial extracellular volume fraction (ECV), a key heart disease biomarker. Results show a correlation between CT-derived and MRI-derived ECV, suggesting CT
Area of Science:
- Cardiovascular Imaging
- Radiology
- Biomedical Engineering
Background:
- Myocardial extracellular volume fraction (ECV) is a vital imaging biomarker for detecting various heart diseases.
- Accurate ECV measurement is crucial for early diagnosis and management of cardiac conditions.
Purpose of the Study:
- To assess the feasibility of estimating myocardial ECV using cardiac computed tomography (CT).
- To evaluate the correlation between CT-derived ECV and the established MRI-derived ECV.
Main Methods:
- Dual-source CT system was used to acquire pre-contrast and delayed-phase images for ECV calculation.
- Cardiac MRI with a modified Look-Locker inversion recovery sequence on a 3T system was used for reference ECV.
- ECV was analyzed across 24 myocardial segments in 8 patients without clinical coronary artery disease.
Main Results:
- A correlation was observed between CT-derived and MRI-derived ECV measurements.
- This indicates the potential of cardiac CT for quantifying myocardial ECV.
Conclusions:
- Cardiac CT demonstrates feasibility for estimating myocardial ECV.
- CT-derived ECV shows a correlation with MRI-derived ECV, supporting its use as a potential imaging biomarker.
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