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    Ankylosing spondylitis is a chronic inflammatory arthritis affecting 200,000 people in the UK. This condition primarily impacts the spine and is diagnosed in approximately 2,300 new cases annually in England and Wales.

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    Area of Science:

    • Rheumatology
    • Immunology

    Background:

    • Ankylosing spondylitis (AS) is a chronic inflammatory disease.
    • It primarily affects the axial skeleton, leading to spinal inflammation and potential fusion.
    • AS is a significant cause of chronic back pain and disability.

    Purpose of the Study:

    • To provide essential facts and statistics regarding ankylosing spondylitis in the UK.
    • To highlight the prevalence and incidence of AS in England and Wales.
    • To describe the basic characteristics of the condition, including its inflammatory nature and demographic distribution.

    Main Methods:

    • Data compilation from epidemiological sources.
    • Analysis of diagnostic statistics for England and Wales.
    • Review of established medical literature on AS.

    Main Results:

    • Approximately 200,000 individuals in the UK live with ankylosing spondylitis.
    • Around 2,300 new diagnoses occur each year in England and Wales.
    • The condition is roughly three times more prevalent in men compared to women.

    Conclusions:

    • Ankylosing spondylitis represents a substantial public health concern in the UK.
    • Understanding the epidemiology of AS is crucial for healthcare planning and resource allocation.
    • The higher incidence in men warrants further investigation into potential contributing factors.