Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genetic Screens02:46

Genetic Screens

5.8K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
5.8K
Karyotyping01:17

Karyotyping

69.7K
Overview
69.7K
Intellectual Disability01:29

Intellectual Disability

964
Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
964
Autism Spectrum Disorder01:19

Autism Spectrum Disorder

1.5K
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
1.5K
Meiosis I01:49

Meiosis I

221.1K
Meiosis is a carefully orchestrated set of cell divisions, the goal of which—in humans—is to produce haploid sperm or eggs, each containing half the number of chromosomes present in somatic cells elsewhere in the body. Meiosis I is the first such division, and involves several key steps, among them: condensation of replicated chromosomes in diploid cells; the pairing of homologous chromosomes and their exchange of information; and finally, the separation of homologous chromosomes by...
221.1K
Learning Disabilities01:25

Learning Disabilities

718
Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
Dyslexia
Dyslexia is a...
718

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bridging understanding and practice: School community perspectives on mental health in schools in Indonesia.

Global mental health (Cambridge, England)·2026
Same author

Communicating unexpected news to pregnant people living with mental health conditions in fetal medicine (the UNDERSTAND study): Healthcare professionals' perspectives.

PloS one·2026
Same author

Moving beyond good intentions: a qualitative study exploring healthcare professionals' perspectives on delivering equitable prenatal testing in the English NHS.

International journal for equity in health·2026
Same author

Barriers and facilitators to contraception access for South Asian women in high-income, English-speaking countries: a systematic review.

BMC primary care·2026
Same author

Optimising rapid prenatal exome sequencing in the NHS genomic medicine service: the EXPRESS Synopsis.

Health and social care delivery research·2026
Same author

Home caregiving, early learning and the development of preschool-aged children in Vanuatu: A secondary analysis of 2023 Multiple Indicator Cluster Survey data.

PLOS global public health·2026
Same journal

Effect of artificial intelligence on nursing documentation and patient safety.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2026
Same journal

Strategies for responding to anger from patients, relatives and carers.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2026
Same journal

Nurses' role in detecting early and subtle signs of patient deterioration in acute hospitals.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2026
Same journal

Pulse oximetry: exploring its role, limitations and challenges in clinical practice.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2026
Same journal

Anorexia nervosa: identification and management by non-specialist nurses.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2026
Same journal

Skin and soft tissue abscesses: assessment and management.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2026
See all related articles

Related Experiment Video

Updated: Mar 13, 2026

Chromosome Screening of Human Preimplantation Embryos by Using Spent Culture Medium: Sample Collection and Chromosomal Ploidy Analysis
12:32

Chromosome Screening of Human Preimplantation Embryos by Using Spent Culture Medium: Sample Collection and Chromosomal Ploidy Analysis

Published on: September 7, 2021

2.7K

Down's screening: the right to informed choice.

Jane Fisher1

  • 1Charity that provides non-directive information and support to women and couples on antenatal screening and its consequences.

Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
|October 21, 2016
PubMed
Summary
This summary is machine-generated.

Antenatal screening for Down's syndrome is gaining attention, especially with non-invasive prenatal testing (NIPT). This advanced screening offers higher sensitivity for detecting the condition during pregnancy.

More Related Videos

In Vitro Modeling of Down Syndrome Neurogenesis Using Human-Induced Pluripotent Stem Cells
06:38

In Vitro Modeling of Down Syndrome Neurogenesis Using Human-Induced Pluripotent Stem Cells

Published on: March 7, 2025

1.1K
Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
09:30

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

3.6K

Related Experiment Videos

Last Updated: Mar 13, 2026

Chromosome Screening of Human Preimplantation Embryos by Using Spent Culture Medium: Sample Collection and Chromosomal Ploidy Analysis
12:32

Chromosome Screening of Human Preimplantation Embryos by Using Spent Culture Medium: Sample Collection and Chromosomal Ploidy Analysis

Published on: September 7, 2021

2.7K
In Vitro Modeling of Down Syndrome Neurogenesis Using Human-Induced Pluripotent Stem Cells
06:38

In Vitro Modeling of Down Syndrome Neurogenesis Using Human-Induced Pluripotent Stem Cells

Published on: March 7, 2025

1.1K
Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
09:30

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

3.6K

Area of Science:

  • Medical screening technologies
  • Genetics and prenatal diagnostics
  • Public health policy

Background:

  • Down's syndrome screening is a key component of antenatal care.
  • Current screening methods have limitations in sensitivity and specificity.
  • Recent media attention has focused on advancements in prenatal diagnostic capabilities.

Purpose of the Study:

  • To evaluate the sensitivity and implications of non-invasive prenatal testing (NIPT) for Down's syndrome.
  • To discuss the potential integration of NIPT into national healthcare systems.
  • To address the public and clinical discourse surrounding advanced prenatal screening.

Main Methods:

  • Review of current scientific literature on NIPT for Down's syndrome.
  • Analysis of diagnostic accuracy data for NIPT compared to traditional methods.
  • Examination of policy documents and ethical considerations for NIPT implementation.

Main Results:

  • Non-invasive prenatal testing (NIPT) demonstrates significantly higher sensitivity for Down's syndrome detection.
  • NIPT reduces the need for invasive diagnostic procedures, thereby lowering associated risks.
  • Implementation of NIPT requires careful consideration of cost-effectiveness and ethical frameworks.

Conclusions:

  • NIPT represents a major advancement in antenatal screening for Down's syndrome.
  • Widespread adoption of NIPT could improve screening outcomes and reduce procedural risks.
  • Further research and policy development are necessary for optimal integration into healthcare systems.