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Related Experiment Video

Updated: Mar 13, 2026

Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG

Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG

Published on: December 28, 2014

18F-Choline Uptake in Acute Ischemic Stroke.

Kostas Delaunay¹, Florence Le Jeune, Etienne Garin

¹From the Department of Nuclear Medicine, Comprehensive Cancer Center, Rennes, France.

Clinical Nuclear Medicine

|October 21, 2016

Summary

F-choline PET/CT revealed increased uptake in the brain's right temporoparietal junction, likely due to repair processes following a recent ischemic stroke.

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Area of Science:

Neurology
Nuclear Medicine
Radiology

Background:

The case involves a 75-year-old male patient with a history of prostate cancer.
The patient underwent Fluorine-18 choline (FCH) PET/CT imaging.

Observation:

FCH PET/CT demonstrated significantly elevated uptake in the right temporoparietal junction of the brain.
This area was diagnosed with acute ischemic stroke and a distal right middle cerebral artery branch thrombosis three weeks prior.

Findings:

The observed increased FCH uptake in the brain region affected by ischemic stroke suggests active biological processes.
Choline's role in cell membrane repair and growth in neurological conditions provides a potential explanation for the PET/CT findings.

Implications:

This finding highlights the potential of FCH PET/CT to visualize and assess early repair mechanisms post-stroke.
Understanding these metabolic changes could inform future therapeutic strategies for stroke recovery.