Related Experiment Videos
Microcomputer programs for complex epidemiologic procedures. II. Test for equality and trend of adjusted rates.
1Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Rockville, Maryland 20857.
Computers and Biomedical Research, an International Journal
|August 1, 1989
Summary
This study introduces a microcomputer program for analyzing statistically significant dose-response effects of risk factors. It implements a hypothesis test using score statistics for quantitative analysis of adjusted excess rates.
Area of Science:
- Biostatistics
- Epidemiology
- Health Informatics
Background:
- Existing microcomputer programs can compute adjusted excess rates but lack quantitative analysis for risk factor categories.
- Determining statistically significant dose-response effects after adjustment is crucial in risk factor analysis.
Purpose of the Study:
- To present a microcomputer program for computing score statistics for a recently reported hypothesis test.
- To enable quantitative analysis of statistically significant dose-response effects of risk factors.
Main Methods:
- The study implements a hypothesis test based on score statistics derived from a product model for excess rates.
- A microcomputer program is developed to perform the complex iterative computations required for these score statistics.
Main Results:
- The microcomputer program successfully implements the computation of score statistics.
- The application of the program is illustrated, demonstrating its utility in analyzing dose-response effects.
Conclusions:
- The developed microcomputer program facilitates the quantitative analysis of adjusted excess rates.
- It provides a tool for assessing the statistical significance of dose-response relationships in risk factor analysis.