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Elliptic fourier analysis of cell and nuclear shapes
G Diaz1, A Zuccarelli, I Pelligra
1Dipartimento di Citomorfologia, Università di Cagliari, Italy.
Computers and Biomedical Research, an International Journal
|October 1, 1989
Abstract:
The elliptic Fourier analysis (EFA) is proposed to characterize the cell and nuclear shape. The principal feature of this method is that it decomposes shapes with a closed contour into subshapes each of which maintains a closed contour. A set of homogeneous, nonredundant descriptors, independent of the contour rotation and translation, is computed from the elliptic Fourier coefficients. These descriptors also account for the contour size and resolution. The paired analysis of the cell and nuclear shape provides an exhaustive and accurate definition of the nucleoplasmic configuration.