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6-TIPS-β-Cyclodextrin-Modified Fe3 O4 for Facile Enantioseparation of 1-(1-Naphthyl)ethylamine
Lu Wang1,2, Xiang-Yong Liang1,2, Li-Sheng Ding1
1Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China.
Abstract:
A new type of chiral magnetic nanoparticle was prepared from covalently linked magnetic nanoparticles (Fe3 O4 ) and heptakis-(6-O-triisopropylsilyl)-β-cyclodextrin (6-TIPS-β-CD). The resulting selectors (TIPS-β-CD-MNPs) combined the good magnetic properties Fe3 O4 and efficient chiral recognition ability of 6-TIPS-β-CD. The enantioselectivity of TIPS-β-CD-MNPs towards 1-(1-naphthyl)ethylamine was six times higher than that of the parent β-CD modified Fe3 O4 particles.
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